Event Type:

Colloquium

Date/Time:

Monday, March 12, 2018 - 16:00 to 17:00

Location:

GLSN 200

Guest Speaker:

Institution:

Department of Mathematics and Institute of Applied Mathematics, University of British Columbia

Abstract:

I will describe recent progress in interpretation and modeling of super-resolution light microscopy applied to immune cell surface receptor organization and dynamics. The main experimental tools I will describe will be STochastic Optical Reconstruction Microscopy (STORM) and Single Particle Tracking (SPT). Over the last few years I have been working on model-based mathematical and computational methods to understand the information coming from these experimental techniques. In this talk I’ll describe the biological context and experimental set-up, and then move on to show how stochastic modeling approaches based primarily on hidden Markov methods can help with interpretation.

Host: