Event Detail

Event Type: 
Mathematical Biology Seminar
Thursday, February 6, 2014 - 04:00
KIDD 236

Antiretroviral drugs have a clinical benefit of substantially reducing
infectiousness thus making them potentially an important strategy in the
fight against HIV/AIDS. Recent advances in drug therapy have seen the use
of antiretroviral medications as a prophylaxis. In this study, we
constructed a compartmental heterosexual transmission model based on the
dynamics of HIV in heterosexual population in Sub-Sahara.  The model
classifies the male and female populations by risk (low, medium and high)
according to their sexual preferences. Data from South Africa was used to
parameterize the model.  For a finite amount of drugs we implemented a
numerical optimization algorithm to find optimal allocation of the drugs
that minimizes objective functions such as Total Number of Deaths and Total
Number of Infections. Preliminary results suggest that, the priority should
be given to the high-risk females during drug allocations to minimize the
number of deaths or infection per year.