Radiation damage to biological system is a complicated multiscale problem in spatial and temporal perspective. Mathematical modeling has been an effective tool to study radiation effect in radiation biology for a long time. In this work, an integrated spatial and temporal stochastic model is proposed to study the radiation effect on biological cells. The model could be used to create computerized cells, to simulate the radiation transportation process in computerized cells, to quantify the DNA damage production in computerized cells, to quantify the cell state evolution dynamics, and to quantify the biological effect of computerized cells. The model was implemented based on multi-platform simulation.