On February 22, the College of Science gathered to recognize academic, administrative and teaching excellence at the 2021-22 Combined Awards Ceremony. The first portion of the ceremony celebrated research and administrative achievements, while the second highlighted outstanding teaching, advising and mentoring.

The College celebrates the Teaching and Advising Awards winners below for their deep commitment to engaging with the student experience and application of mentoring and advising expertise to ensure student learning and success within and beyond the classroom. Effective teaching, advising and mentorship are the very heart of the College of Science’s identity as a robust and thriving community of students and scholars. Driven almost exclusively by students’ nominations, these awards are an opportunity for our community to express gratitude and appreciation for each other.

2022 Teaching, Advising and Mentoring Award Winners

Olaf Boedtker Award for Excellence in Academic Advising

James Hansen (Mathematics ’20, Actuarial Science Minor) was in 8^th grade when his aunt foretold his future career. “She said, ‘you’re good at math, you should be an actuary,’” he recalls. “I was like, ‘Oh, what’s that?’”

Less than a decade later, Hansen has found a niche as a full-time Actuarial Analyst at GovInvest, aiding government agencies in their fiscal planning. He credits his success to determination and decisiveness: “I stuck to the schedule and hammered it out,” he said of getting an education.

When Hansen entered Oregon State, he was already well on his way to achieving that goal. He earned an associate’s degree at Clackamas Community College while still in high school, taking over 100 credits of general education and advanced math coursework.

Oregon State welcomes and encourages students to earn college credit prior to enrollment and accepts credit earned through a wide variety of options. Our Degree Partnership Program also allows students to enroll at both OSU and any Oregon community college concurrently, minimizing overall college costs and allowing for more flexibility in course scheduling.

For Hansen, this early investment of time and energy allowed him to jump into 300-400 level courses when he came to Oregon State, finishing his B.S. in just two years.

Plugging in to actuarial science

Hansen attended Canby High School outside Portland, where his soccer coach happened to be friends with Oregon State’s Actuary in Residence Manny Hur. Hansen was able to meet Hur for a job shadow and career counseling session. They chatted for a couple hours, “and that was basically the decision right there,” he said of choosing Oregon State.

Once at the College, Hansen found his instructors helpful, accommodating and inspiring — even when it came to graduating during the pandemic.

“Mina Ossiander was just very real with it,” Hansen said of the Professor of Mathematics’s probability courses. “I loved her. I think that there are some professors out there that act like their course was your whole life, but Mina was not that person.” When classes went remote due to COVID, Hansen said Ossiander was respectful of students’ changing needs and challenges in a time of unprecedented instability.

He was also impressed by how Assistant Professor of Statistics James Molyneux handled the transition to remote coursework. “I had him the only term I took online, he was amazing, again just super down to earth, really good speaker, great at teaching, and encouraged conversation between students," Hansen said. “I’d say that online class [Statistics 413] was the best-set-up of any class I took.”

Finishing his degree in two years kept Hansen busy, and biking to class allowed him to build exercise into his schedule. Corvallis and Oregon State are ranked nationally for bike-friendliness, and 30% of Oregon State students opt to bike to campus.

Finding a niche in a small startup

Through participation in the College’s Actuarial Science Club, Hansen found an internship with a large health insurance company right after graduation. While the predictability of working there was convenient, Hansen likes the flexibility and variety of his current position. At software startup GovInvest, “I get to have a lot more impact and say than I would at a larger company,” he said.

Based in Portland, GovInvest advises public institutions and private companies in their pension and benefits planning. “It’s very niche,” said Hansen of his work helping government agencies interface with their employees. “Say a firefighter wants a health benefit when they retire. The city’s not going to know right off the top of their head, ‘oh this is the amount of money we need to have saved up by the time they retire to meet that liability.’ Our work makes it so that there can be a conversation there without just guessing. It provides certainty in very uncertain circumstances.”

Hansen said he likes the non-traditional nature of his work, and the leadership opportunities afforded by running with a small team. “It’s a rewarding accomplishment to see how everything kind of lines up in the end,” he said.

Embracing stability and commitment

What Hansen finds most fulfilling about his work is the freedom it gives him to live a life he loves. Hansen and his wife met in high school, got married in college and recently bought a house together in Molalla. Having their own space with a yard for their dog is a dream that was worth the time and hard work it took to make it happen.

One of the resources that was integral to their success as a young couple in college was the Supplemental Nutrition Assistance Program (SNAP) offered through the Department of Human Services. Hansen said the decision to apply was a game-changer: “we were living off, like, ramen before,” he joked. “And then suddenly we could afford real food!” He encourages students who qualify to take advantage of this program. Assistance with eligibility questions can be found through the OSU Human Services Resource Center.

All along, finding the path to success for Hansen took trust, discipline and a series of decisions — from taking those advanced math classes back in high school, to getting married at 19 and beyond. Hansen said a love for certainty and stability have motivated him along the way.

Yet sometimes college students get stuck in trying to make decisions that will bring them the perfect future they picture — especially when choosing a major. Hansen said getting a degree is sometimes less about making the perfect choice and “more about showing you can just commit to finishing something.” For students wavering between two great options, “just pick something,” he said. “Make a decision, and if that decision turns out not to be the right one, then switch it up.”

Congratulations to the Oregon State College of Science Class of 2021! This class faced enormous challenges due to the pandemic. On the spur of the moment, the class of 2021 transitioned to remote learning, virtual interaction with professors, mentors, peers, friends and experiential learning in online formats. They have also faced increased financial burdens and other stressors. Our students have persevered, showing admirable determination, resilience and fortitude that will serve them well in their lives and careers.

Succeeding against odds while making history, College of Science graduates have found ways during this pandemic to participate and make an impact on state-wide public health endeavors through the TRACE-CVOID-19 project. They have gained enduring skills and done outstanding work in adapted science labs and with science communication in the virtual domain. Our seniors have been instrumental in helping Oregon State succeed at remote teaching in their roles as peer learning assistants and tutors.

Science graduates have led the way by dint of their academic achievements, selfless service and committed leadership. Supported by awards, scholarships and dedicated advisors, our seniors have collaborated with faculty mentors to create new knowledge and achieve major scientific breakthroughs.

Check out our Commencement page to celebrate our graduates. Read their compelling stories below containing reflections on undergraduate experiences at Oregon State and their dreams for the future.

This year’s graduates include Fulbright and Ford Foundation Fellows, Gilman International Scholars, NOAA Scholars, published scientific authors, future doctors, scientists, entrepreneurs, community leaders, teachers and informed, engaged world citizens. We are exceptionally proud of our students and all they have achieved during their career as undergraduates in the College of Science at Oregon State.

By the numbers

The College graduated 670 undergraduate students with baccalaureate degrees in 2020-21, including 68 Honors graduates. More than 80% (538) of our graduates were in the life sciences, with Biology having the most graduates at 199. BioHealth Sciences came in second with 152 graduates; biochemistry and molecular biology had 71 graduates; Zoology 63; Mathematics 56; Microbiology 43; Chemistry 42; Physics 34, and; Biochemistry and Biophysics graduated 10 students.

Of the total baccalaureate graduates, 11% are underrepresented minorities and 26% are first-generation students. In addition, 10 of the 2021 baccalaureate graduates are military veterans.

The College will also award 52 doctoral degrees, 66 master’s degrees and seven certificates in online Data Analytics.

Of the 52 doctoral degrees, Chemistry had 16 Ph.D. students, followed by Integrative Biology at 11; Mathematics 9; Physics 6; Microbiology 5; Statistics 4, and; Biochemistry and Biophysics graduated one doctoral student.

The Department of Statistics awarded 15 master's degrees in statistics and 19 M.S. degrees in data analytics. Chemistry and Mathematics awarded 10 master's degrees each. Physics had 6 master's degree recipients; Microbiology three; Biochemistry and Biophysics two, and; Integrative Biology awarded one master's degree this year.

Celebrating the Class of 2021

We invite you to read the profiles of our seniors. These outstanding graduates represent an inclusive and diverse learning community in the College of Science. Here they share their inspiring and unique journeys as science majors.

• Simone Burton, Integrative Biology
• Devonte Casey, Zoology
• Gabriela Cortes Cortes, BioHealth Sciences
• Ilana Gottfield-Lee, Biochemistry and Molecular Biology
• Rohal Kakepoto, Physics
• Kendra Krebs, Microbiology
• Seth Pinckney, Biochemistry and Biophysics
• Jennifer Smucker, Mathematics
• Linus Unitan, Chemistry

In recognition of the International Day of Women and Girls in Science, held on February 11, we acknowledge the women faculty, students and alumnae of the OSU College of Science. The world’s population is 50% women, and yet only 30% of scientists identify as women.

“Women and girls represent half of the world’s population and, therefore, also half of its potential. Gender equality, besides being a fundamental human right, is essential to achieve peaceful societies, with full human potential and sustainable development.” (Source: https://www.un.org/en/observances/women-and-girls-in-science-day)

The UN main event will take place online. Additionally, the 6th International Day of Women and Girls in Science Assembly will be held at the United Nations Headquarters virtually.

The UN theme for 2021 is “Women Scientists at the forefront of the fight against COVID-19”. The COVID-19 pandemic has disproportionately affected women academics, including women scientists, who may face significant career damage, extending the gender gap in science and highlighting unequal effects and existing systemic inequities. In fact, if we are to learn from past pandemics, women are most affected by pandemics.

The Association for Women in Mathematics (AWM) endorsed an open letter, published by the European Women in Mathematics which emphasized the unequal effects of this pandemic on all women academics, especially untenured women and caregivers. They offered suggestions for universities, government and funding agencies to proactively support their most vulnerable populations.

"We did not experience the crisis equally. Untenured faculty lost more. Women lost more. Caregivers lost more. The more vulnerable the population, the greater the disadvantage. No one chooses a pandemic, but now we can choose how to respond." -- the EWM Standing Committee and the EWM Working Group on the Corona Crisis

It is also important to recognize that we cannot fold the experiences of all women into one. Covid-19 has its deadliest effects at crossroads of differing axes of oppression. To meaningfully address issues of equity and inclusion requires that we respond to the unequal effects at the intersections of race & ethnicity, gender, socioeconomic status, disability, sexual orientation, among other social axes of oppression.

And yet, women have made critical contributions to understanding and combating the virus and mitigating its effects on disadvantaged populations.

During this International day of Women and Girls in Science, we take the opportunity to highlight the contributions of OSU College of Science women, both alumnae and current faculty and students, to the fight against Covid-19.

Science faculty, students and alumnae making a difference

Oregon State University researchers have received a $2 million grant from the David and Lucile Packard Foundation to create a national TRACE Center that will expand the OSU’s COVID-19 public health project to other states.

The center will harness the power of public health departments, universities and other institutions around the country to help measure the prevalence of the virus that causes COVID-19 by combining community surveillance sampling, wastewater analysis, viral sequence data and mathematical models of SARS-CoV-2 prevalence that OSU TRACE researchers have developed.

“In most communities across the country, it is still very hard to get reliable estimates of how many people are actually infected,” said TRACE leader Ben Dalziel, a population biologist in the OSU College of Science. “The TRACE Center will support a network of university-community partnerships that monitor local prevalence and develop new approaches for community-based COVID monitoring. We are extremely grateful to the Packard Foundation for helping us expand this work to other institutions and communities.”

Chad English, Science program officer for the Packard Foundation, said OSU’s TRACE work is different than most coronavirus testing strategies that rely on “trailing indicators” and provide more information about past infections than who is currently infected.

“The TRACE study and its approach to tracking the prevalence and spread of the coronavirus have proven invaluable to communities in Oregon," said English. “With the data and other insights that TRACE provides, public health leaders now have a powerful tool in their hands to better assess the threat of the virus and make decisions in the best interest of their community.

“We at the Packard Foundation are thrilled to support the expansion of this effort to other states and universities around the country.”

Dalziel said more than 100 research universities across the nation have the capacity to help scale up the TRACE project.

“Many universities have untapped capacity to help their states tackle the coronavirus,” he said. “The TRACE team at Oregon State University is looking for universities and public health departments interested in adapting the TRACE model to their states and their communities.”

Anyone interested in partnering on the TRACE project is encouraged to reach out to the TRACE Coordinating Center at [email protected].

Team-based Rapid Assessment of Community-Level Coronavirus Epidemics, or TRACE-COVID-19, was launched by OSU in April with door-to-door sampling in Corvallis, home to Oregon State’s main campus, and expanded to other cities around the state while also adding a wastewater testing component.

In late September, at the start of the academic year, TRACE also started conducting prevalence testing among OSU students, faculty and staff in Corvallis, at OSU-Cascades in Bend and at the Hatfield Marine Science Center in Newport, along with wastewater analysis of effluent from university buildings for COVID-19 viral markers.

“It’s been fantastic to merge sewer surveillance of the virus with the sampling and modeling going on in TRACE,” said project co-leader Tyler Radniecki of the College of Engineering. “Now we have the ability to extend our impact well beyond Oregon’s borders, and that’s a huge opportunity and honor.”

The TRACE project began as a collaboration of five OSU colleges – Science, Agricultural Sciences, the Carlson College of Veterinary Medicine, Engineering, and Public Health and Human Sciences – plus the OSU Center for Genome Research and Biocomputing. The project has functioned in partnership with county health departments around Oregon.

“Oregon State faculty, staff and students have really come together and mobilized to take on the hard work necessary to understand and combat this pandemic,” said OSU epidemiologist Jeff Bethel, also a project co-leader. “And of course we can’t take on this kind of challenge without the kind of support we’re receiving from the Packard Foundation and our other funders.”

PacificSource Health Plans and the Oregon Health Authority have also supported the TRACE project, whose diagnostic testing component operates through a partnership between the Oregon Veterinary Diagnostic Laboratory, which is located at OSU, and Willamette Valley Toxicology.

“One of the most exciting things about this project is that it shows how a land grant university can fulfill its potential to serve communities statewide – and nationally,” said Justin Sanders, a molecular pathologist at the Carlson College of Veterinary Medicine who is overseeing testing operations at the OVDL and is a member of the TRACE leadership team. “This project brings together experts from a broad range of fields motivated to quickly fill a critical public health need, and now we get the chance to take that to the national level.”

The national partnerships and collaborations afforded by the grant from the Packard Foundation, which comes on top of the $1.15 million it contributed to help launch the project, are critical in responding to a disease as widespread and deadly as COVID-19, said Javier Nieto, dean of OSU’s College of Public Health and Human Sciences.

“This pandemic requires all of us to do everything we can to mitigate the spread and damage of COVID-19,” said Nieto, a TRACE co-leader as well as a physician and epidemiologist. “If ever a situation demanded that we pool our resources, both at OSU and around the globe, this is it.”

The data gathered and analyzed by TRACE researchers provide important guidance for local and state officials deciding which public health actions make the most sense in protecting their communities, said Katie McLaughlin, an applied statistician in OSU’s colleges of Science and Agricultural Sciences and another TRACE co-leader.

“Among its other effects, COVID-19 is generating volumes of data that need statistical interpretation so our leaders can use the information for maximum benefit,” McLaughlin said. “Thanks to all of the support we continue to receive, and thanks to Oregon State’s overarching spirit of collaboration and service, we’re able to play a key role in helping communities stay safe.”

TRACE has tested traditionally underserved and racially diverse populations, Dalziel noted, adding that outreach materials and messaging have been made available in a variety of languages.

“We want to engage communities to get folks tested who might not otherwise be getting tested and as rapidly as possible,” Dalziel said. “We seek to have our samples be truly representative of the whole community, not just a portion of the community. In partnering with communities to monitor prevalence rapidly, we are achieving something that hasn’t been done very many other places during this pandemic. We hope the value of this approach appeals to others as well.”

The College of Science is proud to announce that 41 science students – a record number – have received summer undergraduate research awards that will provide the opportunity and funding to pursue their research ambitions.

Undergraduate research often plays an instrumental role in developing student-faculty relationships that help students learn and grow beyond the scope of the classroom. For many OSU students, these awards provide the financial leverage to work in the field they are passionate about without being constrained to jobs that simply pay the bills.

The Summer Undergraduate Research Experience (SURE) award is available to all science students who meet the academic requirements. Participants are paid for 11 weeks of full-time research, or 440 hours, for a maximum of $5060. Awardees also receive an additional $500 for research expenses, including travel costs, materials or equipment rental.

This is also the second year that the Department of Integrative Biology offered the Alexei Lubchenco Menge Fellowship, which was awarded to Lily Miksell to support her research examining the interactions of dominant foundation species in Oregon rocky intertidal communities under the guidance of integrative biology professor Sally Hacker. The fellowship was established in memory of Alexei Lubchenco Menge, who died at age 27 in 2005. The award seeks to help one student each year within the department who exemplifies the deep love of the ocean that Lubchenco Menge personified.

SURE science awards are made possible by generous donations of College of Science alumni, faculty and supporters.

The COVID-19 pandemic has led to come changes in the SURE science program in 2020. Due to COVID-19 restrictions limiting access to laboratory space at Oregon State University, the deadline for completing SURE scholar research projects was extended to May 2021. Some students have projects that can be done entirely remotely and will complete and present their findings by the end of the summer. Some of the students below are able to work on their projects in OSU labs this summer, following OSU and Oregon Health Authority safety guidelines. For the majority of this year's awardees, the extended timeframe will allow them an opportunity to continue their research safely throughout the school year while gaining research experience.

SURE Science Scholars

Juan Altamira | Chemistry | Vince Remcho

Analysis of Explosive Compounds via Paper Microfluidic Device

Roy Anderson | Biology | Bruce Menge

Examining the Effects of Upwelling Intensity and Recruitment Limitation on Successional Trajectories in the California Current Large Marine Ecosystem

Thao Mi Anthony | BioHealth Sciences | Kyriakos Stylianou

Implication of Metal Organic Framework with Nanoparticle Composites to Deliver Medication

John Barnes | Biology | Felipe Barreto

Quantity and Quality of DNA extracted from dry vs. alcohol preserved samples of China rockfish

Elizaveta ‘Leeza’ Bliznyuk | BioHealth Sciences | Dylan Nelson

Targeting Mycobacterium abscessus pre-existing biofilms

Madeline Bloom | Chemistry | Claudia Maier

Microchip-MS Optimization of Oxylipins Analysis as a Biomarker for Cardiovascular Disease

Elizabeth Brennan | Microbiology | Stephen Giovannoni

Plankton Need Their Vitamins: Vitamin B1 Excretion by Marine Synechecoccus

Russell Campbell | Zoology | Robert Mason

Integrative Biology Collections Management

Dustin Campbell | Zoology | Robert Mason

Sexual Dimorphic growth of Harderian glands in Thamnophis sirtalis

Emily Gemmill | Biochemistry & Molecular Biology | Weihong Qiu

Keeping up with the kinesins: analyzing regulatory proteins and their effects on the motility of KlpA, a kinesin-14 motor protein

Jessica Giulietti | Biology | Patrick Chappell

Exploring regulation of osteosarcoma in vitro: Mechanisms of RANKL production by autocrine neuropeptides

Dylan Gregory | Biology | Virginia Weis

Using the Split Luciferase Complementation Assay to Identify Protein-Protein Interactions In Cnidarian-Algal Symbiosis

Joshua Griffis | Biochemistry & Molecular Biology | Richard Cooley

Optimized Phosphoserine tRNA Selection

Shelby Hansen | Biology | Brittany Poirson

How is a young mussel's life affected by coastal water conditions?

Joshua Havelind | Biology | Francis Chan

Effect of rising temperature in the ocean on Dungeness Crabs

Toren Ikea-Mario | Biochemistry & Molecular Biology | Tory Hagen

Glutathiones effect on Mitochondrial Decay

Rohal Kakepoto | Physics | Janet Tate

Hall Measurements of TiO2 Polymorphs

Rony Koluda | Chemistry | Claudia Maier

Low Dose Radiation Effect on Myelination -Associated Proteins in Mice

Chapman Kuykendall | Biochemistry & Molecular Biology | Colin Johnson

Characterizing the Biophysical Interactions between Dysferlin C2A and the H3 Helix of Syntaxin-4

Dustin Campbell | Biochemistry & Molecular Biology | Massimo Bionaz

In vivo-in vitro dose-effect response of bovine liver to rumen-protected fatty acids: implementation of a nutrigenomic approach in dairy cows

Jessica Li | Chemistry | Jan Stevens

The effects of xanthohumol on gut microbial metabolism

Maya Livni | Biochemistry & Molecular Biology | Maude David

Unraveling the impact of the gut microbiota metabolites on intestinal sensory neuronal cells and how EECs transduce signals to the brain by forming a synapse with the vagus nerve

Ruben Lopez | BioHealth Sciences | Bo Sun

Quantifying ECM Remodeling by Invasive Tumors

Christopher Markgraf | Biochemistry & Molecular Biology | Susanne Brander

Immortalization and Validation of Inland Silverside Cardiomyocytes, Hepatocytes, and Osteoblasts

Saki Nakai | Mathematics | Vrushali Bokil

Mathematical Modeling of Bipolar Disorder

Hunter Nelson | Physics | Tuan Pham

Blowup of Reaction Diffusion Equations

Jacob North | Biochemistry |Victor Hsu

Elucidating binding features of drug targets to Farnesoid X receptor by unsupervised machine learning of molecular dynamics trajectories

Sarah Olson | Microbiology | Frederick Colwell

Investigating Changes in the Microbiome of North Creek

Reina Paez | Biochemistry & Molecular Biology | Lia Danelishvili

Identifying and Purifying Non-Tuberculosis Mycobacterial Surface Antigens for the Purpose of Inducing Trained Immune Responses in Macrophages

Aneila Parra | Biology | Jiraporn Lueangsakulthai and David Dallas

Premature vs. Term Infant Milk Protein Digestome

Jacob Rauenhorst | Chemistry | Kathy Magnusson

Effects of ibuprofen on NMDA receptor expression and contribution

Alan Schultz | Physics |Hoewoon Kim

The Linearized Navier-Stokes Equations Solved on the Sphere by Fourier Transform Method

Rhea Sellitto | Biology | James Rivers

Evaluating the nutritional landscape for wild bees in managed conifer forests

Anna Sung |BioHealth Sciences| Maria Franco

Role of Redox Signaling in Development and Growth of Tumors of the Nervous System

Savannah Taggard | Biology | Molly Burke

The evolution of RoundUp resistance in the yeast Saccharomyces cerevisiae

Jessica Waymire | Physics | Matt Graham

Hyperspectral Fluorescence Imaging of Twisted Bilayer Graphene

Kaytlin Wearne | Biochemistry & Molecular Biology | Kenton Hokanson

The Effects of hsp90 on p2x7 on Human ALS Neurons

Devin Wright | Biochemistry & Molecular Biology | Michael Freitag

Zymoseptoria Tritici Mutation Accumulation Experiment

Elizaveta "Lisa" Zhivaya | Biochemistry & Biophysics | Maude David

Impact of the gut microbiota metabolites on the autism phenotype modulation

How can we better understand how devastating plant diseases are spread? Is there a better statistical model to predict HIV prevalence in a city? Is there a way we can detect toxic algae blooms in freshwater and marine ecosystems before they occur? And of the hundreds of thousands of different metal-organic frameworks (MOFs) in the world, how can we can better find the ones that are most useful for storing and separating gases, like CO2 from industrial plants?

Curiosity is critical for discovery. Asking the questions above led five faculty members to receive College of Science Research and Innovation Seed (SciRIS-ii) and Betty Wang Discovery Fund awards this February to pursue answers over the course of the next year. Their proposals all showed transformative potential and progress toward new frontiers of science and aimed to strengthen collaboration with external research partners. Below is more detail about each of their proposals.

Mathematics Professor Vrushali Bokil was awarded $8,000 to use modeling techniques to understand the spread and control of plant diseases caused by coinfecting viruses. She will focus on Maize Lethal Necrosis (MLN), an emerging disease in Kenya and other parts of Africa that is caused by coinfecting viruses and spread by insects called Thrips, as a test case. Her team’s goals are to use stochastic models and optimal control theory to understand the mechanisms that drive patterns of coinfection in plant populations and effective techniques for controlling the spread of disease in crops and natural grasslands.

In collaboration with the Centers for Disease Control and Prevention (CDC), Statistics Assistant Professor Katherine McLaughlin received $10,000 to explore the use of new statistical methodologies to estimate the number of people who inject drugs in metropolitan areas. The research project, supported by the privately-funded Disease Mechanism & Prevention Fund at the OSU Foundation, has a goal of refining current methods to produce improved population-level demographic, behavioral, disease prevalence and population size estimations. This will aid the CDC in their efforts to contain or slow the rate of HIV in metropolitan areas across the U.S.

Microbiologist Kimberly Halsey was awarded $10,000 to examine the potential for real-time, automated volatile organic compound (VOC) detection as early-warning signals of toxic harmful algal blooms (HABs) in freshwater and marine ecosystems. HABs are increasing in intensity and severity due to climate change and nutrient loading from agriculture and other human-related activities. Some HABs can become toxic to humans and animals. Halsey will use data integration to merge aquatic microbiome data with environmental properties and VOC signatures to identify determinants and trajectory of the annual toxic HAB at Upper Klamath Lake, Oregon.

Physicist David Roundy was also awarded $10,000 to develop new flat histogram Monte Carlo molecular simulation methods to accelerate the discovery of metal-organic frameworks (MOFs) for applications in storing and separating gases. MOFs are crystalline materials that harbor nano-sized pores that have the potential to be used in a variety of clean energy applications, from hydrogen and natural gas storage to capturing carbon dioxide from coal-fired power plant flues. His study aims to enable scientists to accurately predict the absorption properties of hundreds of thousands of MOFs and accelerate the rate of MOF discovery for clean energy applications.

In addition, chemistry professors Kyriakos Stylianou and May Nyman, along with Todd Miller from the Advanced Technology and Manufacturing Institute (ATAMI), received $30,000 from the Betty Wang Discovery Fund to purchase a microwave reactor to integrate on the continuous flow reactor to accelerate the discovery and production of inorganic materials like MOFs. The Betty Wang Discovery Fund supports equipment acquisitions and laboratory infrastructure improvements to advance fundamental discoveries in science. Microwave heating has recently emerged as a powerful method for the preparation of inorganic materials at the laboratory scale, reducing synthesis time down to a few minutes without affecting the product quality or reaction yield. The new machinery will allow the team to investigate the potential of new MOFs to capture carbon in laboratory and industrial applications.

The projects will run for one year, ending next February 2021.The SciRIS program provides funding in three stages for high impact collaborative proposals that build teams, pursue fundamental discoveries and create societal impact. The awards range from $10,000 to $125,000 for various stages of the program and are supported in part by generous alumni and friends, and grants from the U.S. Department of Defense and National Institutes of Health.

The mysteries of human health and disease are as numerous as they are elusive. They pose complex problems that demand complex solutions. As science becomes increasingly interdisciplinary, the edges blurring and blending faster than we can name those evolutions, the challenges of human health require that we examine them from multiple perspectives, from biohealth, bioinformatics and biochemistry to chemistry, mathematics and biology.

In the 21^st century, human health and disease require that we as scientists working in the life, physical and mathematical sciences collaborate. That we put our heads together, step outside the traditional academic boundaries to ignite new thinking and spur innovative solutions to address the most pressing problems in human health.

The proliferation of data is transforming the scientific landscape. Scientists are grappling with how to analyze and integrate data quickly across disciplines. With the mounting need for better, faster ways to harness vast amounts of information, mathematical and statistical researchers make for natural partners who are well trained to manage and interpret data to deepen understanding of the scale of health issues. This approach enables scientists to test more theories and manage more data to develop a greater, more sophisticated understanding of human health.

This fall the National Science Foundation’s Division of Mathematical Sciences and the National Institutes of Health’s National Library of Medicine launched a Joint Initiative on Generalizable Data Science Methods for Biomedical Research to support the development of innovative and transformative mathematical and statistical approaches to address data-driven biomedical and health challenges.

OSU researchers are harnessing the power of global collaborations to deepen understanding of and to address our most important concerns in human health.

The chemistry behind aging

Biophysicist Elisar Barbar and team discovered that the intrinsically disordered state of the protein ASCIZ, a key transcription factor in cells, plays a major role in regulating production of the protein LC8, a hub protein regulating over 100 other proteins critical to a wide range of life processes from viral infection to tumor suppression to cell death. Her work on intrinsically disorganized proteins, a hot frontier of research in biochemical and medical research today, has far-reaching implications due to their critical role in a vast array of cellular functions.

Colleagues Afua Nyarko and Viviana Perez are studying the chemistry behind the biological processes and the synthesis of biologically active molecules. Nyarko studies protein interactions and their role in the formation of tumors. She is one of a handful of scientists worldwide studying proteins from a structural biology perspective, where detailed information on the structure of specific amino acids can reveal how tumor suppressor proteins inhibit specific growth-promoting proteins.

Perez studies the biological processes of aging, specifically the protein aggregation in neurodegenerative diseases and protein misfolding. She discovered a new function for the compound rapamycin that, with its unusual properties, may help address neurologic damage.

Barbar and Nyarko’s work uses nuclear magnetic resonance to describe molecular structures of proteins. They also focus on protein informatics, from the analysis of experimental mass-spectrometry evidence for proteins to the integration and curation of large-scale data warehouses of protein sequence and functional annotation.

Genetics and bioinformatics

Our bioinformatics researchers are working on groundbreaking developments at the nexus of data science and human health. David Hendrix developed a neural network program that illuminates connections between mutant genetic material and disease. His team used deep learning to decipher which ribonucleic acids (RNA) have the potential to encode proteins, an important step toward better understanding RNA, one of life’s fundamental, essential molecules. Unlocking the mysteries of RNA means knowing its connections to human health and disease.

Hendrix compares it to a tool similar to calculus or linear algebra, but one used to learn biological patterns. Deep learning is helping his team manage vast amounts of data and learn new biological rules that distinguish the function of these types of molecules. He recently teamed up with the Barbar group to develop an algorithm that will predict new proteins that interact with LC8. This validates the importance of LC8 in many systems and opens up new interactions to study, underscoring the power of big data to guide new experiments.

David Koslicki recently discovered that the blood of patients with schizophrenia features genetic material from more types of microorganisms than the blood of people without the debilitating mental illness. His team performed whole-blood transcriptome analyses on 192 people, including healthy people and people with schizophrenia, bipolar disorder and Lou Gehrig’s disease. The findings showed that microbiota in the blood are similar to ones in the mouth and gut. There appears to be some permeability there into the bloodstream.

Koslicki and his collaborators received an NIH grant to build a biomedical translator, a software system that connects various distributed databases of biomedical knowledge and that can “reason” over these data sources to answer relevant biomedical questions. This is one example of how mathematical and computational sciences are syncing with biomedical research to accelerate translation for the scientific community.

Fighting disease

Microbiologist Bruce Geller scored a monumental win against antibiotic resistance. He crafted a compound known as a PPMO that genetically neutralizes a pathogen’s ability to thwart antibiotics. His team designed and tested PPMOs against Klebsiella pneumonia, an opportunistic pathogen that’s difficult to kill and resistant to many antibiotics. A platform technology, PPMOs can be quickly designed or modified to kill nearly any bacterium. They are not found in nature so bacteria have not developed resistance to them. PPMOs may be highly effective therapeutics.

Geller expects that the wave of the future will be molecular medicine, a broad field that draws on physical, chemical, biological, bioinformatics and medical techniques to describe molecular structures and mechanisms, identify molecular and genetic errors of disease and develop interventions. OSU scientists are combining these experimental and mathematical tools to develop anti-viral drugs.

Microbiologist Thomas Sharpton made a key advance toward understanding which of the trillions of gut microbes may play important roles in how humans and other mammals evolve. His global team created a new algorithm and software to taxonomize and clarify key microbial clades, or groups of microbes that appear frequently across mammalian species. A Western lifestyle tends to reduce microbial diversity so knowing which clades have been evolutionarily conserved opens up potential health interventions.

The College of Science is launching a transformative program to support and strengthen innovation and entrepreneurship that will enable us to better identify, validate, and develop the commercial impact of basic research. Innovation Days will bring together faculty, faculty research assistants and research associates to discuss and learn about moving basic research ideas and discoveries from the lab to commercial applications and practical solutions.

Co-hosted by the College of Science and the Office of Commercialization and Corporate Development (OCCD), Innovation Days will host its first session on January 7, 2019, 2:30-5 pm followed by a reception from 5-6 p.m. The deadline to register is December 14, 2018. Additional sessions to follow on February 4, April 1 and April 29.

Innovation Days is designed to build awareness and engagement with experts who will help advance and propel the OSU innovation enterprise. Workshop participants will learn about resources to:

• Leverage basic research and research funding opportunities toward application
• Increase the impact of basic research through patents and commercialization
• Validate broader impacts of research projects to enhance proposal success
• Connect with local innovation ecosystem and identify pathways to translate research to application
• Create opportunities with industry
• Integrate invention disclosures, patent applications, and company formation into day-to-day work to advance your career

Facilitators represent and support the many pathways available to successfully transfer technology and commercialize scientific research. The workshop series includes: Berry Treat, director of OCCD, who will provide an overview of his office and how it supports the research to industry pathway; Joe Christison, senior intellectual property and licensing manager at OCCD, who will introduce participants to technology transfer at OSU; Katie Pettinger, commercialization catalyst at OSU Advantage Accelerator, who will discuss startup support available to OSU researchers; chemistry professor Rich Carter, who will share his success story as an inventor; and Chris Stoner, senior industry contracts manager, OCCD, who will discuss the development of appropriate and effective research agreements with companies.

The College of Science’s efforts to advance engagement with science at all levels have been steadily gaining momentum thanks to the incredible contributions of our faculty and students. As a College, we continue to show that science does not have to be confined to an ivory tower, but can and must be used to inform the public about the complexities of life and the world we live in.

Several of this year’s notable accomplishments have been in global research and national and international recognition of our faculty and students.

The research our faculty and students are engaged in demonstrates their passion for the environment, sustainability, oceans, human health, and the data that underlie and illuminate those areas. Our faculty and students are committed to improving the world around us by making it better than how we found it. The year was marked by groundbreaking research on ocean acidification, earthquake forecasting, the dangers affecting coral reefs and more.

Our scientists made key research advances in curing disease from the discovery of a bacterium that kills melanoma cells to successfully combating drug resistance in certain infections. Science faculty and students have won national and international awards and recognition for their extraordinary achievements in improving undergraduate education and innovative research. We look forward to building on this trajectory of growth and momentum this year and beyond.

Highlights of 2017-18

Awards and leadership

• Mathematician Elise Lockwood receives MAA Award for Research in Undergraduate Mathematics Education.
• Great story of how a Japanese musician recreated Mas Subramanian’s YInMn blue to help the children of Fukushima still battling the devastating nuclear powerplant meltdown in 2011.
• A graduate student determines that size is the main factor in predicting how calcifying organisms will respond to ocean acidification.
• Chemistry professor named a 2018 Fellow by the American Chemical Society.
• We hosted 22 area high-school students interested in STEM at Juntos Chemistry Camp in June where they enjoyed liquid nitrogen ice cream and the chemistry behind it through hands-on lab work.
• Biophysicist Weihong Qiu solved a longstanding puzzle concerning the design of molecular motors, paving the way toward new cancer therapies.
• Team Math, including a group of mathematics instructors, received the 2018 Faculty Senate Student Learning and Teamwork Award for creating and sustaining an exemplary learning environment in mathematics courses.
• A 2018 math graduate landed job offers by two Major League Baseball teams—Texas Rangers and New York Yankees, thanks to his expertise in baseball analytics.
• Two Ph.D. students received prestigious NSF Graduate Research Fellowship Program awards for 2018 for 2018.
• Two of seven students at OSU to win Fulbright Scholarships in 2018 were science students!
• Statistics Professor Javier Rojo received the 2018 Dr. Etta Falconer Award for Mentoring and Commitment to Diversity.
• Two math and biology professors were named 2018 OSU Advance Faculty Fellows to advance diversity and equity in STEM fields.
• Physics department head Heidi Schellman was selected to lead a commission of the International Union for Pure and Applied Physics.
• Professor of Physics Janet Tate was named a Distinguished Professor at OSU, bringing our total to 20, more than any other college.
• Distinguished professor of marine ecology Jane Lubchenco received the prestigious National Science 2018 Vannevar Bush Award for her exceptional lifelong leadership in science and technology and substantial contributions through public service in science, technology and public policy.
• Mathematics Professor Juan Restrepo was one of the 28 researchers chosen from around the globe as a 2018 Fellow for the Society of Industrial and Applied Mathematics (SIAM) for his outstanding research and service for the community.
• Biology professor Sally Hacker was elected an AAAS Fellow for her distinguished contributions to coastal ecology.
• Delaney Smith, a junior biochemistry and biophysics major, received the Barry Goldwater Scholarship for 2018, the top undergraduate award in the country for sophomores and juniors in STEM. She was the only Goldwater Scholar selected from an Oregon institution this year.

Teaching and innovation

• We were one of three universities to receive a national award from the American Physical Society for improving undergraduate physics education in 2018.
• Science faculty awarded prestigious $1M HHMI grant to develop culturally inclusive pedagogies in STEM programs.
• Mathematics faculty replaced the traditional classroom model to improve student success in introductory algebra courses by integrating technology, new active learning approaches and measurement of student performance and understanding. These have improved retention, performance and student engagement in 100- and 200-level mathematics classes at OSU.
• In partnership with Ecampus, biology faculty helped create a groundbreaking, first-of-its kind 3-D Virtual Microscope and online introductory biology course series, winning a 2017 WCET Outstanding Work (WOW) award for technology-based solutions that transformed the college learning experience.

Student Success

• We graduated 5% more science students than 2017!
• We launched an Integrated Professional Development platform featuring innovative career preparation programs with content delivered in first-year experience science courses that help to build students’ professional skills and give them a competitive edge in the job market or in graduate school.
• A biohealth sciences major founded OSU’s first pre-osteopathic student club that earned national recognition as Chapter of the Year, from the parent organization Student Osteopathic Medical association, in its first year of operation.

Research

• Statistics research showing how better short-term earthquake forecasting and risk assessment is possible.
• Our statisticians led by Yuan Jiang received a grant to innovate statistical methods to study the human microbiome and its role in human health.
• The Department of Mathematics received its first ever NIH grant—a $437K award from the National Center for Advancing Translational Sciences to build a Biomedical Translator, which is a software system that connects distributed databases of biomedical knowledge and has the capability to “reason” over these data sources to answer relevant biomedical questions.
• A mathematics professor used statistical models to show how the concept of uncertainty in climate science is often misrepresented in public and political discussions.
• Mathematics research by David Koslicki recently showed that the blood of schizophrenia patients features genetic material from more types of microorganisms than that of people without the debilitating mental illness.
• Astrophysicist Davide Lazzati proved that short gamma-ray bursts do follow binary neutron star mergers, confirming that last fall’s union of two neutron stars caused a short gamma-ray burst.
• Our microbiologists advanced the fight against drug resistance, crafting a compound that genetically neutralizes a pathogen’s ability to thwart antibiotics.
• Chemistry professor Sandra Loesgen and graduate students identified a type of soil-dwelling bacterium that produces molecules that induce death in melanoma cells.
• The Department of Integrative Biology hosted the 9th International Symbiosis Society Congress this summer which attracted 400 scientists from around the world to OSU.
• Our microbiology department received a $404K grant renewal to continue to support graduate students studying fish health thanks to the Oregon Department of Fish and Wildlife (ODFW). The 13-year fruitful collaboration benefits fish health and sustainable economic growth in Oregon as well as produces graduates that are now setting policies to ensure a healthy resource well into the future.
• Biology professors are part of an international research group that found that for reef-building corals, not just any symbiotic algae. Their research shows the dangers faced by coral reefs due to the breakdown in the symbiosis relationship, another danger sign for the world’s coral reefs.
• Our chemists led by May Nyman are part of a five-year, $12.5 million National Nuclear Security Administration grant to study nuclear stewardship.
• Biochemists found that loading nanofiber sutures with vitamin D induces the production of an infection-fighting peptide.